Endocrine Abstracts

Introduction: Acne vulgaris is the most common skin disorder, which may be sometimes the only early clinical manifestation of hyperandrogenemia. Main role in its pathogenesis play: genetical predisposition as well as hormonal and environmental disturbances, which may begin in puberty. It has been widely discussed at what age and what kind of diagnostics should be performed in this area.Aim of the study: Was to evaluate concentrations of selected hormones...

Introduction: Despite recommendations neuroendocrine tumors may still pose diagnostic and therapeutic problems. Patients are referred to specialized centers when their disease has already progressed to generalized stage.Case report: A 64-year old male patient was referred to the Department of Endocrinology at the Pomeranian Medical University in 2013 because of liver metastases. His medical history included a surgical treatment of left lung tumor in 2006...

Introduction: The prevalence of incidentally found adrenal tumors – adrenal incidentalomas (AI) – in imaging procedures and autopsy series is up to 4.5–8.7%. Endocrine and clinical evaluation is carried out to diagnose hormonal function or malignancy of the tumors. Nonfunctional adenomas comprise about 80% of AI. The aim of the study was to identify possible association between various clinical, hormonal and radiological features of nonfunctional AI.<p class...

Introduction: Clinically inapparent adrenal masses (incidentalomas) are detected incidentally by imaging procedures in 0.5–4.5% of the general population. Diagnostic process identifies functional and potentially malignant tumors. Adrenocortical tumors might be the first manifestation of non-classic congenital adrenal hyperplasia (NC-CAH). P30L, V281L and P453S mutations of CYP21 gene are the most common mutations of NC-CAH. The aim of the study was to evaluate the relatio...

Available evidence suggests that unfavorable changes in the distribution of body fat resulting from hormonal imbalance associated with ovarian insufficiency may exert detrimental effects on bone mineral density (BMD). The aim of this study was to verify if densitometrically determined volumes of visceral (VAT), female (FAT) and android (AAT) adipose tissue influence BMD in women with menstrual disorders, and if these relationships are modulated by endocrine factors. The study ...

Introduction: Molecular testing play increasingly a significant role in pre-operative diagnosis of nodular goiter, as standard methods may not give conclusive decision in choosing optimal treatment approach. BRAF gene mutations are often discovered in the cytological specimens among the patients with papillary thyroid cancer. The aim of the study was to assess the incidence of BRAF T1799A mutation in cellular specimens derived from fine needle aspiration biopsy (FNAB)...

Introduction: Neuroendocrine cancer of the ampulla of Vater area belongs to the most rare GEP-neuroendocrine tumors (NET). In the literature, there are few reports of extremely malignant course of this cancer. Among 242 patients with NET from the Department of Endocrinology in 2009–2013, 58 pancreatic NET were discovered, among which seven patients had neuroendocrine cancer of the ampulla of Vater. The aim of this study was to determine the clinical characteristics, stagi...